Despite the past efforts to investigate the plant diversity in Saudi Arabia, there are no extensive studies on the plant species, life forms and chorology of the flora in Al Madinah region. This study was conducted to participate in the assessment of the flora in Al Madinah region that would provide a valuable reference for appropriate conservation and management of area under investigation. The meteorological data and available plants were collected and the taxa were indentified, in addition, their life forms and biogeographic affinities were determined. A total number of 33 plant taxa belonging to 31 genera and 19 families were specified, the ascendancy of plant families were to Leguminosae and Zygophyllaceae. The majority of the recorded species were annual chamaephytes with mono-regional distribution where Saharo-Arabian elements had the highest share to the total flora of the present area. The ration of species per genus is 1.06, that less than of recorded ratio in total area of Saudi Arabia which is 2.6. It is concluded that dry climate tends to increase the percentage of chamaephytes and therophytes that are adapted to the dryness and deficiency of rainfall of the studied region.

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