Objective: This study was designed to analyze the long-term effect of nanocomposite\nfiltek Z350 XT (silica nanoparticles and silane-coated zirconia prior) in restoration of\nanterior tooth defects.\nMethods: 105 patients with anterior teeth defect were randomly divided into observation\nand control group. The observation group was treated with 3M Z350 XT resin composite\nwhile the control group was treated with kerr premisa resin composite. All the\nrestorations in oral cavity were clinically evaluated after 1, 3 and 5 years with reference\nto the modified version of United State public health service criterion.\nResults: One year after restoration, there was insignificant (P>0.05) difference in\nsecondary caries, marginal integrity, marginal discoloration, color suitability and\nstructural morphology between the two groups while after 3 and 5 years of restoration,\nthe caries, edge integrity, edge discoloration, color suitability and structural morphology\nwere significantly (P<0.05) better in observation group than control group. For aesthetics\nsatisfaction, after 1 year of repair there was insignificant (P>0.05) difference between the\ntwo groups while after 3 and 5 years of repair, the aesthetic satisfaction in the observation\ngroup was 98.3% and 88.3% respectively.\nConclusion: Compared to Kerr premisa nano-resin composite, the 3M Z350 XT\nnano-resin was more effective in long-term success restoration of anterior defect teeth\nand more reliable in its repair effects.

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