The purpose of this study is to evaluate the toxic effects of Malathion and Cypermethrin on hormonal indices including thyroid and sex hormones. Method: Nine male rabbits (Oryctologus cuniculus) were intoxicated through oral intoxication of Malathion and Cypermethrin at a dose of 75mg/kg body weight for consecutive seven days. Rabbits were grouped into three groups A, B and C comprised of three animals each. Group A was considered as the control, Group B was the Malathion fed group while C was the Cypermethrin intoxicated group. Both insecticides were fed through 1cc syringe. Blood samples were collected and preserved in a refrigerator for further analysis. Results: demonstrated the toxic influences of both insecticides. Malathion produced an increase of 8.08% in LH and 17.13% in FSH, a decrease of 8.03% in estrogen, 45.59% in progesterone, 32.34% in T3, 2.06% in T4 and 31.72% in testosterone. Cypermethrin caused an increase of 12.72% in LH and 51.82% in FSH, a decrease of 13.39% in estrogen, 7.86% in progesterone, 39.65% in T3, 5.02% in T4 and 39.44% in testosterone.Conclusion: This study reveals that both the insecticide is toxic by causing alterations in the hormonal indices and caused reproductive as well as thyroid abnormalities.

Login to Download PDF

Please login with your Paper ID and password to access the full PDF.

🔑 Login to Download