A 60-year-old male, who was diagnosed with systemic lupus erythematosus (SLE) at 33 years of age and was on maintenance hemodialysis for the last 10 years due to lupus nephritis, was admitted to our hospital due to bacterial meningitis. After the remission of meningitis following antibacterial therapy, the patient developed lumbar vertebral osteomyelitis (VO) followed by iliopsoas abscess (IPA) caused by methicillin-sensitive Staphylococcus aureus; both conditions went into remission with antibacterial therapy and subsequent surgical drainage. Although patients with end-stage renal disease undergoing hemodialysis and those with SLE are susceptible to bacterial infections, this is the first case of a patient on hemodialysis due to lupus nephritis who developed meningitis and VO followed by IPA.

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