📚 Volume 25, Issue 11
📋 ID: exUEyxq
Authors
Mohammed Ubaidullah, Abdullah Rehman, K Durga, Shaik Rahiman, Umrana Mirza
Department of Pathology, College of Medicine, Al Jouf University, Sakaka, AlJouf, Saudi Arabia
Abstract
Background : Triple Negative Breast Carcinomas (TNBC) are breast carcinomas which are negative for Estrogen receptor (ER) Progesterone receptor (PR) and no overexpression of Human Epidermal Growth Factor receptor-2 (HER-2). The five year survival rate for breast carcinomas in general is good but the same is bad for TNBC. TNBC has got worse prognosis compared to hormone positive breast carcinomas. Aim:The aim of present study is to diagnose and classify of breast carcinoma to evaluate the aggressive of TNBC based on ER, PR and Her-2 status of carcinoma breast, to assess the overall prognosis. Materials and Methods: One year study was done at a tertiary care center. Patients of all ages were included. Clinically positive patients were send for Mammography, FNAC and Biopsy and tissue embedding was done. Immunohistochemistry (IHC) was performed to diagnose TNBC cases. Results: During this one year period we received 144 cases of breast carcinoma. Out of these 144 cases, 122 cases (84.73%) were positive for triple whereas, 15.27
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📝 How to Cite
Mohammed Ubaidullah, Abdullah Rehman, K Durga, Shaik Rahiman, Umrana Mirza (2018).
"Diagnosis of aggressive Triple-negative breast cancer (TNBC): A Clinicopathological study".
Wulfenia, 25(11).
