Paper\'s purpose: some medicinal plants have medical properties history through richly bioactive compounds. In this study, we aimed to evaluation the antibacterial activity and phytochemical contains of these medicinal plants by used deep eutectic solvent extraction as a green solvents.\nMethods: We selected three medicinal plants and extracted by three different kinds of deep eutectic solvent. Three methods (DIZ, MIC Alamar blue assay and MBC) were used to determine the antimicrobial activity. Phytochemical compositions, total Phenols and flavonoid content were estimation by using spectroscopy. \nResults: All the medicinal plants used in this study showed a clear different inhibition activity against bacterial strains. the DES2: CHMA for P. odorata extract provided the strongest result of antibacterial activity by using MIC and MBC assay against Staphylococcus aureus, Pseudomonas aeriginosa and Escherichia coli. While DES3: CHLA and DES2: CHMA showed the highest amount of phytochemical contains from all plant kinds used more than DES1: LGH. \nConclusions: In this study, all the medicinal plants extracted by DES had various activities and secondary metabolites which may be have activities against bacterial strain.

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