The objective of the current study was to investigate dynamics of changes of health-related quality of life (HRQoL) during the period of 12 months after endovascular or open repair surgical approaches of abdominal aortic aneurysm (AAA). HRQoL questionnaire (SF-36) was administered to patients prior to and 1 month and 12 months after undergoing AAA intervention. Moreover, all-cause of death was recorded in both of groups over the period of 72 months. The magnitude of any differences in HRQoL scores over the period observed was calculated as an effect size (ES). The results from this study pointed out that endovascular group experienced considerable improvement in the majority of SF-36 domains (especially in mental health-oriented domains), as well as in both composite scores, one month after intervention, but this effect was not sustainable after 12 months. Contrary, the sub-cohort of patients who experienced conventional open aneurysm repair demonstrate predominantly stable quality of life one month after intervention, with considerable tendency to large improvement in all domains of SF-36 after 12 months. These results suggested that estimation of HRQoL following different surgical approaches of AAA could be considered as the most appropriate tool for comprehensive assessment of the effectiveness of AAA surgical management.

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