Objective: To identify possible interferences in the quality of life of ostomized patients. Methods: Study participants were recruited from the Ostomy Association of S�o Jose do Rio Preto, S�o Paulo. Participants of both sexes with ostomy were included. Difficulties in answering the questionnaires were the exclusion criteria. Participants completed the sociodemographic questionnaire and then answered the WHOQOL-BREF questionnaire. Results: 78 individuals participated in the study, with a mean age of 55 years (SD=16 years) and 56 years (SD=15 years) when they underwent the ostomy. It was identified that 66.7% of the participants have a cancer diagnosis and that, despite higher values in the mean responses of cancer patients when compared to the questionnaire domains, no statistical differences were found. The median time from the date of the ostomy to the date of the interview was 7.9 years (SD=7.56 years). The correlation analysis between the time of ostomy and the domains of the questionnaire showed that time did not interfere with the quality of life. Conclusion: The oncological diagnosis does not interfere with the quality of life of the ostomized patient. There is no interference in the time of the ostomy from the first month after the procedure and there is a positive impact when compared to other ostomates or those who have a religion. Specialized care and contact with people who have the same diagnosis contribute to improving the quality of life of these patients.

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