. Korean and American ginseng belong to the genus Panax and have a somewhat similar chemical makeup. Both Korean and American ginseng contain ginsenosides, although they contain different types in different amounts. The present study was designed to evaluate the contents of different bioactive compounds and antioxidant activities of Korean ginseng (Panax ginseng) and American ginseng (Panax quinquefolius) aqueous extract. Free radical scavenging activity, reducing power assay, Hydroxyl radical and Superoxide radical scavenging of Korean ginseng recorded as high as 86%, 87%, 82% and 91% compared to American ginseng root extract. The results showed that total phenolic content (3.27±0.12 mg GA/100g DW), total flavonoids (2.06±0.09 mg/g GAE) and ginsenoside content (218.5±8.14 mg/g DW) in Korean ginseng extract were higher compared to American ginseng. The results of this study indicated Korean ginseng root extract had strongest antioxidant activity compared to American ginseng extract.

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