Schistosomiasis is serious disease worldwide distribute. Controls of Biomphalaria alexandrina snails are important to stop transmit disease. However, there is only one molluscicide, niclosamide, recommended by the World Health Organization. Niclosamide has been used effectively but is toxic to non-target organisms. Some bacteria and fungi are causes of serious diseases. The extensive uses of antibiotics produce resistant strains of bacteria. In this study evaluate some extracts of waste materials from natural origin (date seeds, olive seeds and pomegranate peel) against Biomphalaria alexandrina snails and some types of pathogenic bacteria and fungus. In the present study, the most potent extract as molluscicide is pet-ether extract of date seeds referring to its LC50 and LC95 values were 81.26 & 387.86, respectively. All tested biochemical parameters in this study are affected. Ethanolic extract of olive seed showed a significant antibacterial activity against Proteus sp, Klebsiella sp, and P. aeruginosa. The authors concluded that date seeds pet-ether extract is the most potent as molluscicide and can be used alternate to traditional one in control program. Also, the plant wastes extracts (olive seeds, date seeds and pomegranate peel are good sources of antimicrobial compounds against pathogenic and drug resistance bacterial and fungal strains.

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