Microorganisms are attractive sources of proteases as they can be artificially cultured in large quantities in a relatively short time by established fermentation methods. Microbial proteases have been and will continue to gain global significant prominence, particularly in commercial industries. Microbial alkaline proteases dominates the world enzyme market, accounting for a nearly two-thirds share of the detergent industry. Screening and characterization of these proteases from different sources serves many advantages from both environmental and industrial points of view. Most of the microbial proteases of significant application in detergent industry are bacterial alkaline proteases from genus Bacillus. The major bottleneck has been the screening of wild-type biocatalyst that would be detergent compatible with increase efficiency than what is seen today. Given their role in commercial industries; it is deemed imperative to gather the disperse literature on the current state of the art describing the sources, classification, application and biosynthetic regulation of bacterial proteases. Special emphasis has been given to bacterial alkaline proteases that are detergent compatible.

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