The present study aims to evaluate the therapeutic response of topical use of the fruit of Morinda citrifolia Linn in the healing of infected wounds, analyzing the healing time. 42 Wistar rats were randomly divided into two groups of 21 animals: Group N (Topical cream prepared with the Morinda citrifolia Linn fruit) and Group C (Control). These groups were randomly divided into three subgroups according to the observation period and estimated sacrifice time of 7, 14, and 21 days. The healing volume of the wounds of the animals in the Noni group was statistically significant for the three times of analysis and the animals showed greater weight gain. and the formation of hair follicles in the animals of the Noni group. This study showed that topical use of Morinda Citrifilia Linn allowed an improvement in healing, as it has probable antimicrobial, anti-inflammatory, and analgesic actions without adverse events. There were stimulation of fibrin and collagen during the healing process.

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