Only a few case reports are available on refeeding edema among patients with eating disorders, such as anorexia nervosa. Although the precise mechanisms for the onset of refeeding edema have remained uncertain, changes in the secretion of hormones, such as insulin, induced by refeeding treatment or dietary intake loads have been considered as possible causes. We report two cases of refeeding edema in patients with eating disorders. Case 1 involved a 25-year-old female patient with an eating disorder in whom bilateral lower extremity edema was observed 5 days after increasing dietary intake. Consequently, a diagnosis of refeeding edema was established, which disappeared 2 weeks after dietary and salt restriction without pharmacotherapy. Case 2 involved a 17-year-old female patient with an eating disorder in whom anasarca was observed 4 days after increasing dietary intake and decreasing emesis. A diagnosis of refeeding edema was established, which disappeared 2 weeks after dietary and salt restriction without pharmacotherapy. However, in the latter case, plasma insulin levels remained low at the onset of edema and were slightly higher following resolution.

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