Introduction: In the scenario of retinography (RG) studies due to the incidence of diseases in the fundus of the eye, diabetic retinopathy (RD) stands out with about 34.6%, accounting for 4.8% of the 37 million cases of blindness around the world. In addition, GR is also indicated for the analysis of age-related macular degeneration, glaucoma, peripheral degeneration, toxoplasmosis scarring, retinal vascular occlusions, and other lesions. Objective: To compare the \"Daytona®\" device with the conventional indirect ophthalmoscopy (CIO) method, mainly analyzing the diagnosis and the location of the lesions. Methods: A total of 45 participants were analyzed by means of a prospective longitudinal study, following a comparative model, as shown below, following the rules of Consort. Each patient performed both Daytona® and standard indirect ophthalmoscopy examinations, mainly analyzing the diagnosis and location of the lesions. The present study was approved by the Research Ethics Committee under the number: 1.678.583. A common descriptive statistical analysis was performed with mean, standard deviation and percentage values. Anderson-Darling normality test was applied in all predictors. It was followed by Linear Regression Analysis due to the presence of continuous predictors in relation to the predictor\'s responses, with p <0.05 as being statistically different, with 95.0% CI. Multivariate analysis (Dendogram) was also applied. Results: The results obtained in the present study revealed that Daytona® (DAY) was able to identify 31.1% of the diagnoses of 45 patients diagnosed with the CIO. Despite this, DAY was able to identify other types of lesions and also in other locations in the retina (as a horizontal meridian) in relation to Indirect Ophthalmoscopy. Conclusion: The Daytona® wide-angle retinograph is a great tool for documentation and screening of retinal diseases in patients without pupillary dilatation. However, it has a low ability to identify peripheral lesions, especially in the superior and inferior meridians.

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