Introduction:The pathological processes of pulmonary hypertension and COVID-19 disease are similar. Both are characterized by vascular damage, severe micro thrombosis, and microvascular obliterative disease due to extensive endothelial dysfunction.Objective:It was planned to present the clinical, radiological, and biochemical data of patients with pulmonary arterial hypertension(PAH) and Chronic Thromboembolic Pulmonary Hypertension (CTEPH) diagnosed with COVID-19, who were followed up in our pulmonary arterial hypertension (PAH) center, as well as to assess the survival rates and to investigate the factors impacting survival.Methods: Patients who were diagnosed with COVID-19 between March 2020 and July 2021 and were followed up in the PAH center of our hospital, were included in the study. All information were obtained from the records in the hospital automation system. Results:It was found that 24(7.2%) of the 331 patients who had been followed in the PAH center were diagnosed with coronavirus. The mean age of the patients was determined to be 53.54. It was found that 62.5% of the patients were female,54.2% had the etiology of CTEPH and 41.7% of the patients were in functional class II(WHO-FC II) before being infected with COVID-19.The survival rate was 79.2%. It was found out that the risk of mortality decreased by 0.007 times as the cardiac index increased, and the risk of mortality increased 10,233 times as the functional class increased.Conclusion:Mortality rates due to COVID-19 infection were determined to be higher in PAH/CTEPH patients. The cardiac index values and current functional classes of the patients were associated with survival.
Purpose: The aim of our in vitro study was to investigate the marginal leakage of class V cavities prepared by conventional diamond bur and Er:YAG laser. Materials and methods: 45 single rooted intact extracted human teeth were used. They were randomly assigned into three groups, dependent on the preparation technique: Group I (n=15) – diamond bur + total-etch technique; Group II (n=15) – Er:YAG laser + total-etch technique; Group III (n=15)– Er:YAG laser + laser etching. Microleakage was assessed according to the depth of dye penetration along the restoration at x 15 magnification. Results: None of the procedures investigated on our study completely eliminated the microleakage. The extent of dye penetration was lowest in the laser-treated and acid-etched group (Group II). Conclusions: The results of our study revealed that the laser irradiation can modify the morphology of the cavity walls and increase the bond strength with the composite filling.\n Keywords: Er:YAG laser, cavity preparation, microleakage, composite
Dental caries is one of the most common chronic diseases in the world, affecting 60-90% of school-age children and almost 100% of the adult population. Disease prevention at early ages is a fundamental public health principle and particularly relevant for dental caries. One modern alternative method, gaining popularity in recent years is the application of lasers in clinical practice. Different type of laser systems are used in conservative dentistry in several fields as carious lesions diagnosis, desensitization of hypersensitive teeth, remineralisation of initial carious lesions and dental caries treatment.
This study investigates the effects of climate change on alpine plant communities, focusing on changes in species composition, distribution, and ecosystem dynamics. Using a combination of field surveys and modeling techniques, we assess how temperature increases and altered precipitation patterns are reshaping these sensitive environments. Our findings indicate significant shifts in plant species distribution, with some species migrating to higher altitudes and others experiencing population declines. These changes are affecting ecosystem functions, including nutrient cycling and soil stability. Our research highlights the need for conservation strategies that account for ongoing climatic changes in alpine regions.
Urban expansion poses significant challenges to native plant species, disrupting ecosystems and leading to biodiversity loss. This study examines the ecological impacts of urban expansion on native flora in metropolitan areas, focusing on species diversity, habitat fragmentation, and ecosystem services. Through field surveys and remote sensing techniques, the research highlights critical zones of biodiversity decline and identifies conservation strategies to mitigate adverse effects. The findings underscore the importance of integrating urban planning with ecological preservation to foster sustainable urban ecosystems.
