The objective of the present study was to evaluate the mechanical behavior of two different Morse taper implant systems. Twenty self-locking Morse taper implants, 2.9 mm in diameter (FAC), and 20 Morse taper implants, 3.5 mm in diameter (CM) were divided into two groups (n=10), submitted to strength to failure test, optical microscopic evaluation of fracture, metallographic analysis of the alloy, finite element analysis and strain gauge test. The statistical analysis was performed using the Student’s t-test (?=0.05). The resistance to fracture was statistically different (p<0.001) between FAC (225.0±19.8 N) and CM (397.3±12.5 N). The optical microscopic evaluation showed that implants became fractured in the discontinuity region of the abutment/implant interface, the region of stress accumulation in FEA. Metallographic analysis showed that implants from the FAC group are composed of titanium-aluminum-vanadium alloy. In the strain gauge test, there was no statistical difference (p=0.833) between CM (1064.8±575.04 ?S) and FAC (1002.2±657.6 ?S). Due to a lack of clinical data with respect to the use of these implants, it is recommended that they be used in areas with low masticatory effort.
Abstract\nA microgrid (MG) is an independent power network that uses distributed energy sources preferably renewable sources available to meet the local load demand. MGs are operated with grid or islanded mode. The MG needs fast and efficient controllers for effective power management under variable load and dynamic operating conditions. This paper presents detailed analysis of droop control and an optimization technique for effective control and size reduction of components in MG structure. The controller parameter optimization is obtained using Yin-Yang-Pair optimization with Particle Swarm Optimization (YYPO-PSO). The simulated performance of the proposed system using MATLAB/Simulink is presented to demonstrate the capability of the optimized controller compared with traditional methods.
In the present study, the anti-obesity and hepatoprotrctive effect of the aqueous extract of Moringa oleifera leaves (AEMOL) was investigated using a high fat diet (HFD) induced obese rabbits. AEMOL was subjected to different phytochemical analyses including total phenolic and flavonoid content phenolic compounds and vitamin E profiles were identified by mean of high-performance liquid chromatography (HPLC-DAD). Anti-obesity and hepatoprotective effect of AEMOLwere tested in plasma and liver tissue after chronic administration of HFD in rabbits. Supplementation of obese rabbits with AEMOL resulted in a significant change in body weight, triglycerides, total cholesterol, and LDL level as compared to the HFD-induced obesity. Further AEMOL normalized liver biomarkers, elevated hepatic antioxidant defense capacities by increasing the activities of catalase (CAT), superoxide-dismutase (SOD), and glutathione-peroxidase (GPx), and prevented damage in the hepatic histoarchitecture. The therapeutic potential of AEMOL could be attributed to its richness in bioactive and antioxidant compounds.
To artificially enhance antimicrobial peptide expression in Bombyx mori, we constructed genetically engineered silkworms overexpressing Rel family transcription factor, truncated BmRelish1 (BmRelish1t) and BmRelish2 genes controlled by B. mori cytoplasmic actin 3 promoter by using the piggyBac transposon vector. The BmRelish1t gene contained a Rel homolog domain (RHD), nuclear localization signal (NLS), acidic and hydrophobic amino acid (AHAA) rich region, and death domain (DD), but no ankyrin repeat (ANK) domain. The BmRelish2 gene had RHD and NLS, but no AHAA, ANK, or DD. Chromosome analysis of G1 generations of a transgenic silkworm with EGFP expression confirmed stable insertion of BmRelish1t and BmRelish2. BmRelish1t gene overexpression in transgenic silkworms resulted in higher mRNA expression levels of B. mori antimicrobial peptides and proteins such as lebocin (~19.6-fold), moricin (~9.8-fold), and nuecin (~16.4-fold) than those in normal silkworms. However, transgenic silkworms overexpressing BmRelish2 showed mRNA expression patterns of antimicrobial peptides similar to those of normal silkworms, excluding that of lebocin (~3.9-fold). Moreover, transgenic silkworms overexpressing BmRelish1t showed antibacterial activity against various pathogenic bacteria, while those with the BmRelish2 gene showed no antibacterial activity. Therefore, we suggest that BmRelish1t expression could be useful for the simultaneous production of various antimicrobial peptides in transgenic silkworms.
Neonatal late-onset sepsis is a serious condition due to its high prevalence in neonatal intensive care units (NICUs), especially in newborns. This paper aims to highlight the importance of studies that evaluate the prevalence, factors and etiological agents associated with neonatal sepsis. It is a review of the literature in a systematic way, in the databases Medline, Pubmed, Lilacs, SciELO and VHL (Virtual Health Library) involving principally Brazilian studies. According results obtained in this study, the incidence of neonatal late-onset sepsis varies geographically in several states of Brazil among hospitalized newborns. The development of new research about the occurrence of late-onset neonatal sepsis is relevant for the introduction of actions in neonatal health and offers subsidies for the adequacy of care practices to newborns.
This study evaluated the nature to bacterial infections in a neonatal intensive care unit (NICU) at Zagazig University Hospital, Zagazig , Egypt . Rapid diagnosis and identification of the infectious bacterial pathogens by polymerase chain reaction (PCR) is recommended herein. Out of 70 microbial cultures ordered by physicians from many clinical samples, 50 cultures showed bacterial growth. The 50 bacterial cultures obtained were identified by biochemical methods. They were categorized into 6 groups ; were arranged in the following descending order according to number the identified strains : Escherichia (E.) coli (group 1 , 22 isolates) > Staphylococcus (S.) aureus (group 2 , 10 isolates > Streptococcus (St. ) pneumonia (group 3 , 6 isolates) > St . agalactiae (group 4 , 5 isolates) > St. pyogenes (group 4 , 5 isolates) > Klebsiella (Kb.) pneumonia (group 6 ,3 isolates) . Antibiotic sensitivity profiles showed variability in susceptibility of isolates to the 10 studied antibiotics. Certain virulence genes for selected bacterial strains from each bacterial group were rapidly detected by multiplex PCR ; this indicated that PCR technique could be used as a rapid for identification of infectious bacteria and in turn a diagnostic tool for infectious diseases .It reduces time and personal efforts faced microbiologists throughout biochemical identification.