Background: Hematopoietic stem cell transplantation (HSCT) is successfully used, however, morbidity and mortality rates related to the procedure can be detected throughout its different phases. This study aims to identify therapies in the literature that favor an increase in overall survival of patients submitted to Hematopoietic Stem Cell Transplantation. Methods: This study is a Systematic Review conducted through electronic databases, using descriptors indexed in Medical Subject Headings and their respective Entry terms. The quality of the studies was assessed using the Critical Appraisal Skills Programme (CASP) and the Jadad Scale. Results: 15 articles comprised the final sample from 19,543 articles retrieved. Therapies that presented the best results for overall survival were Cyclophosphamide, Doxorubicin, Vincristine and Prednisone, combined with: Rituximab (R-CHOP); R-CHOP plus Interferon ?-2a; high doses of Melphalan followed by autologous HSCT; Lenalidomide; Cytarabine; and HSCT from umbilical cord blood. Conclusions: There was no agreement on the best therapy for favoring an increase in overall survival of patients who underwent HSCT. It is emphasized that the choice of treatment will exclusively depend on the clinical characteristics and the phase of HSCT in which the patient is at. \nKeywords: Disease-free survival; Myeloid leukemia; Neoplasm, Therapy related; Review; Hematopoietic stem cell transplantation; Bone marrow transplantation.
In this paper, we propose adaptive texts detection and localization algorithms and its real-time VLSI architecture. The main techniques include edge filtering, adaptive threshold, the morphological operator and pixel correlation. The block-based processing rather than pixel-based is employed to improve the text detection accuracy. Results show that the proposed method can attain low false-detection rate compared with the recent paper. Based on the algorithm, VLSI architecture is designed with pipeline schedule using parallel structure. With some special techniques, the memory cells can be greatly reduced. The text processor had been realized by one FPGA chip. The throughput rate can achieve 200M pixels per second, which achieve real-time HDTV requirement. The chip used 25k gates, 7200 RAM cells and 7349 registers.
The aim of the present paper is to discuss the concept of quality in the Common European Framework of Reference (CEFR) (2001) and its impact on language education in Polish higher education. Following Schindler et al. (2015), the authors define quality with reference to purposefulness and transformativity and demonstrate how these two dimensions are reflected in the CEFR, pointing to incongruities in the (non)interface between them. Next, the paper illustrates how these inconsistencies affect the interpretation of quality in language teaching with reference to level C1 in the Polish context of higher education. The analysis of 21 study programmes shows that the influence of the CEFR on the understanding of purposefulness and transformativity in the Polish context can be divided into three chronological phases, i.e. compliance, acceptance and contextualization, amplification, marked by a transition from unwarranted compliance with the incompatible with philological studies standard of the CEFR, through attempts to contextualise the norm in foreign language studies to the construction of the standard which lacks thorough empirical and theoretical grounding. Thus, the authors conclude that the impact of the CEFR, even if considerable, does not lead to enhancing quality in language education.
Smart antenna can effectively increase channel efficiency and decrease signal-to-noise ratio in wireless communication. Digital beamforming is one of the most popular techniques. The purpose of digital beamforming is to detect the direction of arrival of signals in order to reject unnecessary information while maintaining signal of interests. Minimum Variance Distortionless Response (MVDR) is among the traditional schemes of digital beamforming. It minimizes the output power and was considered to be a very effective tool. However, MVDR involves the computation of inverse correlation matrix, which makes the computation very extensive and complicated. A recursive scheme was proposed to compute the inverse correlation matrix, using matrix inversion lemma in the Recursive Least Squares (RLS) algorithm. Simulation results have demonstrated that RLS is significantly faster than MVDR in computational speed. This study also investigates the resolution of detection issues under various noise variances. Experiments were conducted in order to obtain the optimal parameters for detecting signal direction of arrivals.
The recently developing cloud storage schemes are mainly focused on reducing data access time and increasing the level of security of cloud data. Division and Replication of Data in the Cloud for Optimal Performance and Security (DROPS) is one among the schemes which affords high security and less access time by dividing a file into fragments, and replicating the fragmented data over the cloud nodes. In this scheme, no meaningful information is revealed to the attacker since no cloud node has more than one fragment of data. However, the duplicate files uploaded by cloud users may cause huge duplicated fragments in cloud nodes which may degrade the cloud’s performance. A deduplication scheme is proposed in this paper to avoid duplicate file uploading by checking Merkle Hash Tree value of the uploaded contents on servers by searching the key value. This scheme is extended with fog computing for supporting massive file uploading by fog devices. An online updating scheme is required to support small dynamic updates to increase the efficiency of cloud storage. A privacy preserving online updating scheme is proposed along with deduplication scheme by incorporating random masking strategy with Verifiable Fine-Grained Dynamic Data Operations. The security and performance enhancement on DROPS is proposed as SePeCloud. SePeCloud smoothly addresses the security issues with optimal performance on replication cost and computation time. Theoretical evaluation and experimental outcomes show that the proposed method exhibits higher efficiency greater and simplicity than the DROPS methodology.
Production of antiserum either monoclonal or polyclonal in Egypt doesn`t take in serious manner and this situation leads to the high prices of ELISA kits. Viral detection is so important for the imported and exported plant materials. Moreover, viruses that infected potato seeds and the most reliable detection of virus infection are ELISA. For that reason, viral RNAs of potato leafroll virus (PLRV) were extracted from infected potato leaves collected from different regions in Egypt. Specific PCR for PLRV coat protein (CP) amplification was performed and fragment with molecular size 624bp was obtained. In addition, purified PLRV-CP gene was cloned into pCR 2.1-TOPO vector and subcloned into prokaryotic expression vector. The expressed protein was injected into New Zealand white rabbit, and the raised polyclonal antiserum was immunoreactive towards PLRV using indirect ELISA. The results were compared with another standard ELISA kit (Sigma, USA) and it was observed that, ours are in the same quality in comparing with the commercial one. We considered the production of polyclonal antiserum is the first step for built in the industry of antibodies production in our area.
In all the regions of the world, Man has domesticated, through the process of trial and error, certain plants so as to ensure his survival. Plants for medicinal purposes were and still are primary elements among these. In present-day societies, as with those of the past, mainly rural ones, medicinal plants are an integral part of therapeutic practices which are as diverse as they are varied. Martinique has also been affected by this growing worldwide phenomenon of the use of plants in preventive treatments or for benign pathologies. By examining the medicinal floras associated with five historical periods, this paper aims to show the characteristics of the successive pharmacopoeias in taxonomic terms and in terms of physiognomic types.
En México, el manejo de los Residuos Sólidos Urbanos está a cargo de los Municipios, tal y como lo señala el Artículo 115 de la Constitución Política de los Estados Unidos Mexicanos, la cual establece que el servicio de limpia, recolección, traslado, tratamiento y disposición final de residuos es cargo de las entidades municipales. El objetivo de la presente investigación es proponer un modelo económico que, a través estímulos fiscales para el pago del Impuesto Predial en el Municipio de Querétaro, México, impulse la responsabilidad social de reciclaje de RSU. Partiendo de la pregunta de investigación de ¿Cuál es el modelo que integre estímulos fiscales capaces de impulsar la responsabilidad social de reciclaje de residuos sólidos urbanos para el pago el impuesto predial en el Municipio de Querétaro?, se aplica una metodología de estadística descriptiva y se obtiene información documental de fuentes oficiales para realizar el análisis, la conclusión es que el modelo económico para el pago del impuesto predial a través de estímulos fiscales, cuantifica la relación entre la cantidad de reciclaje de residuos sólidos urbanos y el importe a pagar del impuesto predial, estimulando la responsabilidad social del reciclaje en el municipio de Querétaro.
The main objective of this work is to evaluate the natural capital and ecosystem services of the Aquidauana River and the role of the Giant otter (Pteronura brasiliensis) as a flag species to change adverse realities, based on system ecology and emergy synthesis. First, a system diagram was constructed to organize the thinking and the relationships between components and pathways of exchange and resource flow. The second step was to construct the emergy synthesis tables of flows directly from the diagrams. Finally, emergy indices were calculated in order to summarize and relate emergy flows of the economy with those of the environment. Quantities of stored emergy of environmental resources are calculated from the sum of the emergy of all inputs, and then multiplied them by the time it takes to accumulate the storage. To calculate the emergy of economic storages, all inputs of energy, materials, and labor to produce them were summed. For the evaluation of renewable inputs to the Aquidauana River, solar energy, rainfall, runoff, river geopotential, transport of phosphorous, and wind annual averages were used. Main services with market values provided by the Aquidauana River are information, water supply, tourism, and fish harvest.
Electricity provides power that drives automation and industrialization. Most developing countries are experiencing acute power shortages and Nigeria is not an exception. The power situation in Nigeria is so bad that a lot of local industries have been forced to close down. In this work, the state of power generation in Nigeria is surveyed and the current level compared to the level needed to successfully power and industrialize the economy. The results show that for the industrial development of Nigeria, She needs to generate 170MW daily. With sufficient power supply, investment in automation technologies and robotics would boost the productivity and output of local industries thereby creating a buoyant economy.