Equilibrium between 2-CPHBA and protons, transition metals and lanthanides have been investigated at different temperatures (10,20,30 and 400C) by means of potentiometric titrations in 75% v/v dioxane-water and 0.10 M KNO3 as a constant ionic medium. Thermodynamic Parameters (∆G, ∆H and ∆S) have been determined. The plots of thermodynamic Parameters versus ion potential (Z2/r) of the lanthanide elements is not linear as expected from the ionic theory. The thermodynamic functions ∆G and ∆H of the complexes were analyzed in terms of the electrostatic (el) and non-electrostatic (non) components.
Purpose\nEnd-stage renal disease (ESRD) patients consider hemodialysis as an invasive and time consuming procedure. The total success of hemodialysis depends not only on medical parameters, but also on patients’ satisfaction with life (SwL).\n\nMethods\nData were collected in a single hemodialysis center. 59 patients [average age 63,3 (SD=12,3), 19 women (32,2%)] were evaluated in the survey.\nBoth present and expected in 5 years SwL were evaluated by the Cantril ladder, which is a subjective, non-disease specific, self-reported measure.\nWe analyzed factors which may affect SwL: gender, age, marital status, education, months on dialysis, duration of a single hemodialysis, vascular access, kidney graft in the past or graft willingness in the future, fulfillment of medical recommendations, dialysis adequacy: Kt/V, URR, UF.\n\nResults and Conclusions\nCantril ladder is fast, easy to perform and useful tool for SwL measurement.\nWe excluded a relation between neither present nor expected in 5 years SwL and factors like: gender, education, fulfillment of medical recommendations, months on dialysis, kind of vascular access, URR, UF.\nThe results indicated a positive relation between high expected in 5 years SwL and being in a relationship, having kidney graft performed in the past and willingness of kidney graft in the future. \nESRD patients who are not in a relationship, who didn’t undergo kidney graft in the past or don’t desire a kidney graft in the future and eldest ones expect their SwL in 5 years will be significantly lower. To those ESRD patients the psychological support should be addressed firstly.
The work presented concerns different plant-derived molecules that display various functional biological activities and were identified in the beet plant (Beta vulgaris L.) among the others. Ubiquitously expressed under abiotic and/or biotic stress conditions, but also essential during physiological/developmental processes, these compounds were recognized as crucial mediators of plant adaptation/defense systems and thus may be explored in order to improve plant performance via genetic engineering and/or external application. Their versatile function has also been extensively investigated in the human organism in health and disease, as alteration of levels and activities of such bioactive compounds may contribute to several pathologic conditions, as in the case of affected betaine metabolism. Besides, a vast array of beneficial effects was documented for most of them, such as betalain-dependent anticancer, antiinflammatory, antioxidative and detoxifying mechanisms. Others display still underexplored, but promising properties, such as cytotoxic effects of beetin. Potential and multifunctional impact of these substances create new perspectives for more effective exploitation of the beet crop and Beta genetic resources in terms of the most possible profitability for human health in the protection against so-called civilization diseases, as well as for plant well-being and improved crop performance/productivity under changing climate conditions and decreasing agricultural land.
Background: premature ovarian failure is characterized by loss of oocytes, lack of folliculogenesis, ovarian estrogen production and infertility. CD105mesenchymal stem cells derived from bone marrow represents a tool in supporting cellular therapy. Objectives: the present study was conducted to investigate the therapeutic potency of CD105MSCs transplantation for chemotherapy-induced ovarian damage in rats. Methods: CD105MSCs isolated from BM of 10 male albino rats proliferated in vitro. Eighty mature female albino rats were randomly divided into four groups 20 female rat each; Group 1: normal control, Group 2: ovarian failure induced with CTX, Group 3: ovarian failure treated with CD105 MSCs injected in the caudal vein and Group 4: ovarian failure received Pbs solution injected in the caudal vein.. Results: Eight weeks after treatment, FSH and E2 levels were nearly constant in normal control group while in ovarian failure induced group untreated and ovarian failure induced group received saline showed increase of FSH and E2 by the 8th week. Ovarian failure induced group received CD105MSCs showed an increase of FSH and E2 at the beginning of injection with CD105MSCs and by the end of 8th week there was a return of FSH to normal level. The hormonal findings was confirmed by vaginal smear investigation and histopathological examination. The PCR examination of sry gene expression presents an evidence of stem cell incorporation into the ovarian structure. The present study showed that CD105MSCs implantation can ameliorate ovarian function in rats with ovarian damage induced by CTX injection, which results in abnormal estrous cycles confirmed by vaginal smear investigation. Eight weeks after transplantation, ovarian function was improved, as indicated by increased estradiol levels and decreased FSH levels. Conclusion: CD105MSCs may serve as a promising treatment approach in cases of POF.
Algeria is heavily reliant on its hydrocarbon sector, which accounts for 97% of the country’s export revenue and 60% of budgeted resources. However, there has been limited interest from investors to undertake new oil and gas projects in the past three licensing rounds due to repeated project delay resulting from slow government approval, difficulties attracting investment partners, technical problems and legal restrictions concerning foreign investment in Algeria. Further, the country’s security was evoked especially after the 2013 militant attack on the In Amenas gas facility.\nOn the other hand, petroleum experts have related this limited interest to the lack of hydrocarbon potential of the blocks offered. Therefore; to attract more foreign investment to new projects, the Algerian Government has Enacted new contractual and fiscal provisions in 2013 (Law No.13-01 of 20 February 2013 amending Hydrocarbons Law No. 05-07 of 28 April 2005) and increased security presence at all of its oil and gas facilities.
Introduction: Defective apical seals were identified as the main cause of failures in endodontic treatment, and several studies have emphasized the importance of adequate coronal sealing between sessions for successful endodontic therapy. Objective: to evaluate the effects of prey restoration of temporary restorers Coltosol®, Villevie (Villevie) and Obtur (Maquira) on endodontically treated teeth with thin walls. Methods: The present study was divided into two stages. In the first stage of the research, only with the use of Coltosol®, 4 human molars were used, extracted for reasons unrelated to this work. In the second step, 11 human molars were used with temporary cements as follows: 3 Elements with Coltosol; 3 Elements with Obtur; 3 Elements with Villevie; 2 Elements without provisional restorer (control). Results: The expansion of prey of Coltosol caused significant stresses in the remaining coronary structure, it was also noticed that teeth that have walls with thickness of 1 mm can suffer cracks. Still, the effects of Coltosol plug prey expansion have caused more damage to the enamel structure than Villevie® and Obtur® obturators. Conclusion: The effects of Coltosol plug prey expansion have caused more damage to the enamel structure than Villevie® and Obtur® obturators.
Plants are being used for the control of different insect pests from the ancient time. Plant extracts are prepared from different parts of the plants. Fresh leaves of Melia azadirach, and Azadirachta indica; seeds of Pegnum harmala; stem of Salsola baryosma and rhizome of Zingiber officinale were used during the present study to check their repellent and feeding deterrent effects on Alphitobius diaperinus. The aim of the present work was to use such control measures against insects that are safe and environment friendly. The experiments were performed under control condition that is at 30+2°C and 65+5 % R.H. The extracts were used at three concentration rates i.e. 5%, 10% and 15%. Acetone was used as a solvent to prepare concentrations. Repellence assay was performed using area preference method and to study feeding deterrent effect of plant extracts diet incorporation method was used. Significant results were obtained with all treatments of plant extracts. The effect of the treatments was increasing with the increase in time and concentration. Highest repellence was 89.33% with A. indica while highest feeding deterrence was recorded 92.78% with S. baryosma at highest concentration rates. The results suggest that plant extracts can be used as an effective control measure against A. diaperinus.
A taxonomic survey of the vespine wasps (Hymenoptera: Vespidae) was carried out from May, 2014 to October, 2016. During the study, a total of 798 specimens belonging to the subfamily Vespinae were captured representing 5 species under two genera, Vespa tropica, Vespa velutina, Vespa orientalis, Vespa mandarinia and Vespula flaviceps. The three species, Vespa tropica, Vespa orientalis and Vespa mandarinia are for the first time reported from the study area.
Abstract\nBackground/purpose: \nMelatonin attenuates morphine-induced tolerance by inhibiting microglial activation and heat shock protein 27 expression in the rat spinal cord. Here, we examined the gene expression profile in the dorsal horn of spinal cords from morphine-tolerant rats using a microarray-based analysis.\nMethods: \nMale Wistar rats were implanted with two intrathecal catheters. One catheter was used for continuous morphine or saline infusion. On day 7, melatonin or vehicle was injected via a second catheter immediately after discontinuation of the morphine or saline infusion. After 3 hours, morphine or saline was injected, and the antinociceptive response was measured using the tail-flick reflex. The dorsal horn of the lumbar enlargement section of the rat spinal cord was removed for gene expression profiling using microarray and qRT-PCR analyses.\nResults: \nA total of 164 and 80 up-regulated and 18 and 20 down-regulated differentially expressed genes were found in comparisons between morphine-tolerant versus control rat spinal cords and between morphine-tolerant + melatonin-pretreated versus morphine-tolerant rat spinal cords, respectively. Continuous intrathecal morphine infusion caused antinociceptive tolerance and down-regulated Fkbp6, Prx and Mpz expression in the rat spinal cord dorsal horn. Melatonin pretreatment partially restored the antinociceptive effect of morphine and reversed the gene down-regulation observed in the morphine-tolerant rats. \nConclusion: \nAltered Fkbp6, Prx and Mpz expression is associated with morphine tolerance, and melatonin attenuates antinociceptive tolerance to morphine and reverses Fkbp6, Prx and Mpz down-regulation. We suggest that melatonin pretreatment can be a therapeutic adjuvant for patients who need long-term opioid treatment for pain relief.
Earthworm diversity was investigated in Bahawalpur area from October, 2014 through September 2015. Four habitat types designated as site “I”, “II”, “III” and “IV” were sampled using hand sorting technique randomly. Total of 1,211 specimens were recorded representing one family Megascolicidae, one Genus Pheretima and three species Pheretima posthuma, pheretima burliarensis and pheretima bournei. Pheretima posthuma was the most dominant species among all the species found at the four study sites. Pheretima posthuma had the maximum mean density of 116.33±10.50 per m2 whereas pheretima bournei had the least density 0.67 ± 1.15 per m2 only at one site II during winter season whereas overall, pheretima burliarensis had the least density at all sites. The maximum density was seen during the rainy season under the least disturbed green shady vegetation and minimum density was found during the winter season. The statistical analysis results showed that overall Earthworm diversity (1-D=0.374) on the Simpson’s scale was 37% and on the Shannon scale (H/ln S E=0.624) was 62.4%. It is concluded that these findings are seemed to be helpful to find out earthworm species diversity.
Team cohesion has long been the focus of the attention in sports and business, and over the years, due to its influence on organizational harmony and goal achievement. Previous studies on its influential factors tended to focus on team members\' self-concept, mental health, thinking styles, and emotional management which are verified to contribute to team cohesion respectively. However, in the real world, these factors exist concurrently and may create comprehensive influence on team cohesion.\nThe present study drawing on Nonaka and Takeuchi’s SECI knowledge conversion model and Bandura\'s Reciprocal Determinism attempted to identify their interactive effects and influential structure on team cohesion. The data were obtained from a survey of 287 experienced practitioners in business organizations of Taiwan using 5 fully validated and reliable instruments.\nThe findings of the study revealed the following: (1) The four intrapersonal traits were coexistent with and interdependent on one another, i.e. a small change may create successive chain effects; (2) Individuals\' self-concept played a fundamental role; that is, although it did not enhance team cohesion in a direct manner, it enhanced team cohesion through hierarchical and progressive mediating effects; and (3) Individual’s emotional management, as a mediator factor, was the dominant factor affecting the quality of team cohesion in the real business world. In summary, these findings suggest that team cohesion can be enhanced through cultivating team each member’s perspectives and intrapersonal traits.
To discern the care stress levels that foreign care workers of various nationalities experience when administering care, and determine the correlation between their care stress and quality of life (QoL). In addition, the effects of care stress and overwork on QoL, the influence of QoL on wellbeing, and their various correlations are examined. This study engaged in a cross-sectional study by using a structured questionnaire method to survey 300 caregivers in Yunlin County who were employed in workplaces such as households or nursing homes, and were responsible for providing care to patients of stroke. The questionnaires included demographic information, and scales measuring care stress, overwork, QoL, and wellbeing. The research procedures were reviewed and approved by the Institutional Review Board of the Tri-Service General Hospital (1-105-05-059), after which data were collected. Of the 300 distributed questionnaires, 291 completed questionnaires were returned, yielding a response rate of 97.0%. The research model estimated by the Smart PLS M3 program was used to interpret the structural relation results. The research findings demonstrate that care stress and overwork negatively impact caregiver QoL. Notably, QoL is more positively correlated to their wellbeing. Care stress and overwork are correlated to the QoL of caregivers who take care of patients with stroke, and caregiver QoL is correlated to their own wellbeing. In addition, QoL influences wellbeing more widely in terms of scope. Governments should continue to promote residential respite care, which can assist caregivers in gaining rest, alleviate their work stress, and improve their QoL and wellbeing.
A special place in stomatology and maxillo-facial surgery belongs to chronic non-specific conditions of salivary glands. Chronic development of these conditions, difficulties in achieving remissions list the problems of accurate diagnosing, treatment and prevention of exacerbation of chronic non-specific sialadenitis amongst complicated medical issues, requiring further investigation.\n Identification of microflora with further determination of its sensitivity to antiomicrobial medications, as well as the use of justified immunotherapy that facilitates the correction of specific resistance of the organism, could significantly improve the efficiency of the treatment of the chronic non-specific sialadenitis.\nThe goal of the research was the improvement of the efficiesny of the integrated treatment of patients with chronic non-specific sialadenitis through combined use of autoleucocites, stimulated by immunomodulator immunophane and the antimicrobial medications of targeted action.\nWe performed the examination and treatment of 112 patients with salivary glands’ diseases during 2014-2016 in the department of stomatology and maxilla-facial surgery of the ASITD after A. Aliyev. The pool consisted of 46 patients with chronic non-specific sialdeinitis (15 males and 31 females) applied during the exacerbation. The age of patients with different types of chronic non-spesific sialdenitis was between 18 and 82 years. The control groups consisted of 25 persons with no pathology of salivary glands and somatic conditions.\nIt was noted that the efficiency of treatment of chronic non-specific sialdenitis is higher during the administration of integrated treatment, consisting of antibiotics that the microorganisms are highly sensitive to, and the immunotrophic medication. . It was noted that the use of autoleucocites, stimulated by immnophane had lead to normalizing most of indicators of the immune status, leading to stabilization and improvement of the condition of patient, as confirmed by subjective data and clinical and laboratory outcomes. As a result, the remission period is extended and the disease is transformed from active form in to inactive.\n The summary of the results of our study allows to say that pathogenic microflora and disturbance of immunity play and important role in the ethiology and pathogenesis of chronic non-specific sialadenitis (sialodchitis, parenchimatous and instersticial). An integrated approach to the treatment of chronic nonspecific sialadenitis, including anti-microbial and immune modulating therapy determines its efficiency in terms of decrease or complete elimination of clinical signs of the disease with significant extension of remission.